POLR3K Antibody
Product Sizes
50ul
£312.00
OAAN01832-50UL
100ul
£451.00
OAAN01832-100UL
200ul
£718.00
OAAN01832-200UL
About this Product
- SKU:
- OAAN01832
- Additional Names:
- C11;C11-RNP3;DNA-directed RNA polymerase III subunit K;DNA-directed RNA polymerase III subunit RPC10;DNA-directed RNA polymerases III 12.5 kDa polypeptide;HLD21;My010;polymerase (RNA) III (DNA directed) polypeptide K; 12.3 kDa;polymerase (RNA) III subunit K;RNA polymerase III 12.5 kDa subunit;RNA polymerase III subunit C10;RNA polymerase III subunit C11;RNA polymerase III subunit CII;RPC10;RPC11;RPC12.5.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs; such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts; such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
- Gene Details:
- RNA polymerase III subunit K
- Host:
- Rabbit
- Immunogen:
- POLR3K
- Isotype:
- IgG
- Molecular Weight:
- 12kDa
- Protein Details:
- DNA-directed RNA polymerase III subunit RPC10
- Purification:
- Affinity purified against immunogen
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
