ACY1 Antibody
Product Sizes
50ul
£264.00
OAAN01745-50UL
100ul
£379.00
OAAN01745-100UL
200ul
£581.00
OAAN01745-200UL
About this Product
- SKU:
- OAAN01745
- Additional Names:
- ACY-1; ACY1D; HEL-S-5
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- This gene encodes a cytosolic; homodimeric; zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group; and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1; a region reduced to homozygosity in small-cell lung cancer (SCLC); and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart; and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency; a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene; as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.
- Gene Details:
- aminoacylase 1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human ACY1
- Isotype:
- IgG
- Molecular Weight:
- 45 kDa
- Protein Details:
- Aminoacylase-1
- Purification:
- Affinity purified against immunogen
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
