BEST1 Antibody
Product Sizes
50ul
£264.00
OAAN01483-50UL
100ul
£379.00
OAAN01483-100UL
200ul
£581.00
OAAN01483-200UL
About this Product
- SKU:
- OAAN01483
- Additional Names:
- ARB; BMD; BEST; RP50; VMD2; TU15B; Best1V1Delta2
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2); also known as Best macular dystrophy; in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
- Gene Details:
- bestrophin 1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human BEST1
- Isotype:
- IgG
- Molecular Weight:
- 67 kDa
- Protein Details:
- Bestrophin-1
- Purification:
- Affinity purified against immunogen
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
