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Antibodies

ACTL6A Antibody

Product Sizes
50ul
£264.00
OAAN01251-50UL
100ul
£379.00
OAAN01251-100UL
200ul
£581.00
OAAN01251-200UL
About this Product
SKU:
OAAN01251
Additional Names:
Arp4; ACTL6; BAF53A; INO80K; ARPN-BETA
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
This gene encodes a family member of actin-related proteins (ARPs); which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold; which is an ATP-binding cleft; as a common feature. The ARPs are involved in diverse cellular processes; including vesicular transport; spindle orientation; nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals; which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin; it is required for maximal ATPase activity of BRG1; and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
Gene Details:
actin like 6A
Host:
Rabbit
Immunogen:
Recombinant protein of human ACTL6A
Isotype:
IgG
Molecular Weight:
47 kDa
Protein Details:
Actin-like protein 6A
Purification:
Affinity purified against immunogen
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody