ABAT Antibody
Product Sizes
50ul
£264.00
OAAN01179-50UL
100ul
£379.00
OAAN01179-100UL
200ul
£581.00
OAAN01179-200UL
About this Product
- SKU:
- OAAN01179
- Additional Names:
- GABAT; NPD009; GABA-AT
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA); an important; mostly inhibitory neurotransmitter in the central nervous system; into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation; hypotonia; hyperreflexia; lethargy; refractory seizures; and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
- Gene Details:
- 4-aminobutyrate aminotransferase
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human ABAT
- Isotype:
- IgG
- Molecular Weight:
- 56 kDa
- Protein Details:
- 4-aminobutyrate aminotransferase; mitochondrial
- Purification:
- Affinity purified against immunogen
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
