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Antibodies

TP53 Antibody

Product Sizes
50ul
£264.00
OAAN01086-50UL
100ul
£379.00
OAAN01086-100UL
200ul
£581.00
OAAN01086-200UL
About this Product
SKU:
OAAN01086
Additional Names:
P53; BCC7; LFS1; BMFS5; TRP53
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
This gene encodes a tumor suppressor protein containing transcriptional activation; DNA binding; and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes; thereby inducing cell cycle arrest; apoptosis; senescence; DNA repair; or changes in metabolism. Mutations in this gene are associated with a variety of human cancers; including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons.
Gene Details:
tumor protein p53
Host:
Rabbit
Immunogen:
Recombinant protein of human TP53
Isotype:
IgG
Molecular Weight:
44 kDa
Protein Details:
Cellular tumor antigen p53
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody