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Antibodies

CSF1R Antibody

Product Sizes
50ul
£264.00
OAAN01017-50UL
100ul
£379.00
OAAN01017-100UL
200ul
£581.00
OAAN01017-200UL
About this Product
SKU:
OAAN01017
Additional Names:
FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; BANDDOS; M-CSF-R
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
The protein encoded by this gene is the receptor for colony stimulating factor 1; a cytokine which controls the production; differentiation; and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL); HL cell lines and anaplastic large cell lymphoma.
Gene Details:
colony stimulating factor 1 receptor
Host:
Rabbit
Immunogen:
A synthetic peptide of human CSF1R
Isotype:
IgG
Molecular Weight:
108 kDa
Protein Details:
Macrophage colony-stimulating factor 1 receptor
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20°C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody