HLA-DQA1 Antibody
Product Sizes
50ul
£264.00
OAAN00768-50UL
100ul
£379.00
OAAN00768-100UL
200ul
£581.00
OAAN00768-200UL
About this Product
- SKU:
- OAAN00768
- Additional Names:
- DQA1; DQ-A1; CELIAC1; HLA-DQA
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB); both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes; dendritic cells; macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities; resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
- Gene Details:
- major histocompatibility complex; class II; DQ alpha 1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human HLA-DQA1
- Isotype:
- IgG
- Molecular Weight:
- 28 kDa
- Protein Details:
- HLA class II histocompatibility antigen; DQ alpha 1 chain
- Purification:
- Affinity purified against immunogen
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
