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Antibodies

CYP1A1 Antibody

Product Sizes
50ul
£264.00
OAAN00760-50UL
100ul
£379.00
OAAN00760-100UL
200ul
£581.00
OAAN00760-200UL
About this Product
SKU:
OAAN00760
Additional Names:
AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
This gene; CYP1A1; encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol; steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs); some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however; it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member; CYP1A2; is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene Details:
cytochrome P450 family 1 subfamily A member 1
Host:
Rabbit
Immunogen:
Recombinant protein of human CYP1A1
Isotype:
IgG
Molecular Weight:
58 kDa
Protein Details:
Cytochrome P450 1A1
Purification:
Affinity purified against immunogen
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody