FGFR2 Antibody
Product Sizes
50ul
£264.00
OAAN00708-50UL
100ul
£379.00
OAAN00708-100UL
200ul
£581.00
OAAN00708-200UL
About this Product
- SKU:
- OAAN00708
- Additional Names:
- BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- Varies by lot. See vial for exact concentration.
- Extra Details:
- The protein encoded by this gene is a member of the fibroblast growth factor receptor family; where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic; basic and/or keratinocyte growth factor; depending on the isoform. Mutations in this gene are associated with Crouzon syndrome; Pfeiffer syndrome; Craniosynostosis; Apert syndrome; Jackson-Weiss syndrome; Beare-Stevenson cutis gyrata syndrome; Saethre-Chotzen syndrome; and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
- Gene Details:
- fibroblast growth factor receptor 2
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FGFR2 (NP_000132.3).
- Isotype:
- IgG
- Molecular Weight:
- 110 kDa
- Protein Details:
- Fibroblast growth factor receptor 2
- Purification:
- Affinity purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20°C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
