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Antibodies

SFTPC Antibody

Product Sizes
50ul
£264.00
OAAN00560-50UL
100ul
£379.00
OAAN00560-100UL
200ul
£581.00
OAAN00560-200UL
About this Product
SKU:
OAAN00560
Additional Names:
SP5; SP-C; PSP-C; SFTP2; SMDP2; BRICD6
Clonality:
Polyclonal
Extra Details:
This gene encodes the pulmonary-associated surfactant protein C (SPC); an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA; SPB; SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified; which cause pulmonary surfactant metabolism dysfunction type 2; also called pulmonary alveolar proteinosis due to surfactant protein C deficiency; and are associated with interstitial lung disease in older infants; children; and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
Gene Details:
surfactant protein C
Host:
Rabbit
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-197 of human SFTPC.
Isotype:
IgG
Molecular Weight:
21 kDa
Protein Details:
Pulmonary surfactant-associated protein C
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody