CD274 Antibody
Product Sizes
50ul
£264.00
OAAN00448-50UL
100ul
£379.00
OAAN00448-100UL
200ul
£581.00
OAAN00448-200UL
About this Product
- SKU:
- OAAN00448
- Additional Names:
- B7-H; B7H1; PDL1; PD-L1; hPD-L1; PDCD1L1; PDCD1LG1
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells; such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue; this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments; this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies; including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.
- Gene Details:
- CD274 molecule
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human CD274
- Isotype:
- IgG
- Molecular Weight:
- 33 kDa
- Protein Details:
- Programmed cell death 1 ligand 1
- Purification:
- Affinity purified against immunogen
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
