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Antibodies

BCL2L1 Antibody

Product Sizes
50ul
£290.00
OAAN00021-50UL
100ul
£379.00
OAAN00021-100UL
200ul
£581.00
OAAN00021-200UL
About this Product
SKU:
OAAN00021
Additional Names:
BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S
Clonality:
Polyclonal
Conjugate:
Unconjugated
Extra Details:
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane; and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential; and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria; both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
Gene Details:
BCL2 like 1
Host:
Rabbit
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human Bcl-XL (NP_612815.1).
Isotype:
IgG
Molecular Weight:
26 kDa
Protein Details:
Bcl-2-like protein 1
Purification:
Affinity purified against immunogen
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20°C. Avoid repeated freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody