ATF6 Antibody
Product Sizes
50ul
£264.00
OAAN00015-50UL
100ul
£379.00
OAAN00015-100UL
200ul
£581.00
OAAN00015-200UL
About this Product
- SKU:
- OAAN00015
- Additional Names:
- ACHM7; ATF6A
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Extra Details:
- This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor; this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer; and following ER stress-induced proteolysis; it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations; but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis.
- Gene Details:
- activating transcription factor 6
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human ATF6.
- Isotype:
- IgG
- Molecular Weight:
- 75 kDa
- Protein Details:
- Cyclic AMP-dependent transcription factor ATF-6 alpha
- Purification:
- Affinity purification.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C. Avoid repeated freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
