WRN Antibody
Product Sizes
100 ug
£582.00
OAAL00355-100UG
About this Product
- SKU:
- OAAL00355
- Additional Names:
- DNA helicase; RecQ-like type 3;exonuclease WRN;recQ protein-like 2;RECQ3;RECQL2;RECQL3;Werner syndrome ATP-dependent helicase;Werner syndrome RecQ like helicase;Werner syndrome; RecQ helicase-like.
- translate.label.attr.clone:
- 2F7
- Clonality:
- Monoclonal
- Extra Details:
- This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism; including transcription; replication; recombination; and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity; and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing; this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome; an autosomal recessive disorder characterized by premature aging. [provided by RefSeq
- Gene Details:
- WRN RecQ like helicase
- Host:
- Mouse
- Immunogen:
- WRN (NP_000544; 1322 a.a. ~ 1432 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Isotype:
- IgG1 Kappa
- Protein Details:
- Homo sapiens Werner syndrome RecQ like helicase (WRN); mRNA|Werner syndrome ATP-dependent helicase [Homo sapiens]
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
