BEST1 Antibody
Product Sizes
100 ug
£582.00
OAAL00353-100UG
About this Product
- SKU:
- OAAL00353
- Additional Names:
- ARB;BEST;Best disease;Best1V1Delta2;bestrophin-1;BMD;RP50;TU15B;vitelliform macular dystrophy protein 2;VMD2.
- translate.label.attr.clone:
- 1C2
- Clonality:
- Monoclonal
- Extra Details:
- This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2); also known as Best macular dystrophy; in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms
- Gene Details:
- bestrophin 1
- Host:
- Mouse
- Immunogen:
- VMD2 (AAH41664; 361 a.a. ~ 460 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Isotype:
- IgG1 Kappa
- Protein Details:
- BEST1 protein [Homo sapiens]|Homo sapiens bestrophin 1; mRNA (cDNA clone MGC:47884 IMAGE:5194649); complete cds
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
