RASA1 Antibody
Product Sizes
100 ug
£582.00
OAAL00277-100UG
About this Product
- SKU:
- OAAL00277
- Additional Names:
- CMAVM;CM-AVM;CMAVM1;GAP;p120;p120 RAS GTPase activating protein;p120GAP;p120RASGAP;PKWS;ras GTPase-activating protein 1;RAS p21 protein activator (GTPase activating protein) 1;RASA;RASGAP;triphosphatase-activating protein.
- Clonality:
- Monoclonal
- Extra Details:
- The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function; the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS; thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Alternative splicing results in two isoforms where the shorter isoform; lacking the N-terminal hydrophobic region but retaining the same activity; appears to be abundantly expressed in placental but not adult tissues. [provided by RefSeq
- Gene Details:
- RAS p21 protein activator 1
- Host:
- Mouse
- Immunogen:
- RASA1 (NP_002881; 948 a.a. ~ 1047 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Isotype:
- IgG1 Kappa
- Protein Details:
- Homo sapiens RAS p21 protein activator 1 (RASA1); transcript variant 1; mRNA|ras GTPase-activating protein 1 isoform 1 [Homo sapiens]
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
