NFKBIB Antibody
Product Sizes
100 ug
£582.00
OAAL00215-100UG
About this Product
- SKU:
- OAAL00215
- Additional Names:
- ikappaBbeta;I-kappa-B-beta;ikB-B;IKBB;ikB-beta;NF-kappa-B inhibitor beta;NF-kappa-BIB;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor; beta;thyroid receptor-interacting protein 9;TR-interacting protein 9;TRIP9;TRIP-9.
- translate.label.attr.clone:
- 1G6
- Clonality:
- Monoclonal
- Extra Details:
- NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910); RELA (MIM 164014); or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA; MIM 164008; or NFKBIB); which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA; MIM 600664 or IKBKB; MIM 603258) marks them for destruction via the ubiquitination pathway; thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A; C; or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM
- Gene Details:
- NFKB inhibitor beta
- Host:
- Mouse
- Immunogen:
- NFKBIB (AAH15528; 1 a.a. ~ 356 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Isotype:
- IgG2a Kappa
- Protein Details:
- Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor; beta; mRNA (cDNA clone MGC:9440 IMAGE:3903794); complete cds|Nuclear factor of kappa light polypeptide gene e
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
