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Antibodies

MRE11A Antibody

Product Sizes
100 ug
£582.00
OAAL00200-100UG
About this Product
SKU:
OAAL00200
Additional Names:
ATLD;AT-like disease;DNA recombination and repair protein;double-strand break repair protein MRE11;double-strand break repair protein MRE11A;endo/exonuclease Mre11;HNGS1;meiotic recombination 11 homolog 1;meiotic recombination 11 homolog A;MRE11 double strand break repair nuclease A;MRE11 homolog 1;MRE11 homolog A; double strand break repair nuclease;MRE11 homolog; double strand break repair nuclease A;MRE11 meiotic recombination 11 homolog A;MRE11 meiotic recombination 11-like protein A;MRE11A;MRE11B.
translate.label.attr.clone:
3H4-F4
Clonality:
Monoclonal
Extra Details:
This gene encodes a nuclear protein involved in homologous recombination; telomere length maintenance; and DNA double-strand break repair. By itself; the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase; this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Gene Details:
MRE11 homolog; double strand break repair nuclease
Host:
Mouse
Immunogen:
MRE11A (AAH05241; 1 a.a. ~ 206 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Isotype:
IgG2a Kappa
Protein Details:
Homo sapiens MRE11 meiotic recombination 11 homolog A (S. cerevisiae); mRNA (cDNA clone IMAGE:3997666); complete cds|MRE11A protein [Homo sapiens]
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody