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Antibodies

MCM6 Antibody

Product Sizes
100 ug
£582.00
OAAL00190-100UG
About this Product
SKU:
OAAL00190
Additional Names:
DNA replication licensing factor MCM6;MCG40308;MCM6 minichromosome maintenance deficient 6 (MIS5 homolog; S. pombe);minichromosome maintenance deficient (mis5; S. pombe) 6;Mis5;P105MCM.
translate.label.attr.clone:
7D8
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2; 4 and 7 proteins possesses DNA helicase activity; and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity; suggesting a role in the regulation of DNA replication. [provided by RefSeq
Gene Details:
minichromosome maintenance complex component 6
Host:
Mouse
Immunogen:
MCM6 (NP_005906.2; 1 a.a. ~ 821 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Isotype:
IgG2a Kappa
Protein Details:
DNA replication licensing factor MCM6 [Homo sapiens]|Homo sapiens minichromosome maintenance complex component 6 (MCM6); mRNA
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody