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Antibodies

MCM3 Antibody

Product Sizes
100 ug
£582.00
OAAL00189-100UG
About this Product
SKU:
OAAL00189
Additional Names:
cervical cancer proto-oncogene 5;DNA polymerase alpha holoenzyme-associated protein P1;DNA replication factor MCM3;DNA replication licensing factor MCM3;HCC5;hRlf beta subunit;MCM3 minichromosome maintenance deficient 3;minichromosome maintenance deficient 3;P1.h;p102;P1-MCM3;replication licensing factor; beta subunit;RLF subunit beta;RLFB.
translate.label.attr.clone:
2H3
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with; and thus is acetlyated by MCM3AP; a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. [provided by RefSeq
Gene Details:
minichromosome maintenance complex component 3
Host:
Mouse
Immunogen:
MCM3 (NP_002379; 699 a.a. ~ 808 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Isotype:
IgG2a Kappa
Protein Details:
DNA replication licensing factor MCM3 isoform 1 [Homo sapiens]|Homo sapiens minichromosome maintenance complex component 3 (MCM3); transcript variant 1; mRNA
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody