ABCC2 Antibody
Product Sizes
100 ug
£582.00
OAAL00048-100UG
About this Product
- SKU:
- OAAL00048
- Additional Names:
- ABC30;ATP-binding cassette sub-family C member 2;ATP-binding cassette; sub-family C (CFTR/MRP); member 2;canalicular multidrug resistance protein;canalicular multispecific organic anion transporter 1;CMOAT;cMRP;DJS;MRP2;multidrug resistance-associated protein 2.
- translate.label.attr.clone:
- 2H6
- Clonality:
- Monoclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1; MDR/TAP; MRP; ALD; OABP; GCN20; White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore; this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS); an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq]
- Gene Details:
- ATP binding cassette subfamily C member 2
- Host:
- Mouse
- Immunogen:
- ABCC2 (NP_000383; 214 a.a. ~ 313 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Isotype:
- IgG1 Kappa
- Protein Details:
- canalicular multispecific organic anion transporter 1 [Homo sapiens]|Homo sapiens ATP binding cassette subfamily C member 2 (ABCC2); mRNA
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
