CASP10 Antibody
Product Sizes
100 ug
£582.00
OAAL00039-100UG
About this Product
- SKU:
- OAAL00039
- Additional Names:
- ALPS2;apoptotic protease MCH-4;CASP-10;caspase 10 apoptosis-related cysteine peptidase;caspase 10; apoptosis-related cysteine protease;caspase-10;FADD-like ICE2;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE2;FLICE-2;ICE-like apoptotic protease 4;interleukin-1B-converting enzyme 2;MCH4.
- translate.label.attr.clone:
- 3C9
- Clonality:
- Monoclonal
- Extra Details:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits; large and small; that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7; and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
- Gene Details:
- caspase 10
- Host:
- Mouse
- Immunogen:
- CASP10 (NP_116756.2; 19 a.a. ~ 187 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Isotype:
- IgG2a Kappa
- Protein Details:
- caspase-10 isoform 2 preproprotein [Homo sapiens]|Homo sapiens caspase 10 (CASP10); transcript variant 2; mRNA
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
