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Antibodies

BMPR2 Antibody

Product Sizes
100 ug
£582.00
OAAL00028-100UG
About this Product
SKU:
OAAL00028
Additional Names:
BMP type II receptor;BMP type-2 receptor;BMPR3;BMPR-II;BMR2;bone morphogenetic protein receptor type II;bone morphogenetic protein receptor type-2;bone morphogenetic protein receptor; type II (serine/threonine kinase);BRK-3;POVD1;PPH1;T-ALK;type II activin receptor-like kinase;type II receptor for bone morphogenetic protein-4.
translate.label.attr.clone:
4A2
Clonality:
Monoclonal
Extra Details:
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs; which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors; but they require their respective type I receptors for signaling; whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension; both familial and fenfluramine-associated; and with pulmonary venoocclusive disease. [provided by RefSeq
Gene Details:
bone morphogenetic protein receptor type 2
Host:
Mouse
Immunogen:
BMPR2 (NP_001195.2; 939 a.a. ~ 1037 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Isotype:
IgG2a Kappa
Protein Details:
bone morphogenetic protein receptor type-2 precursor [Homo sapiens]|Homo sapiens bone morphogenetic protein receptor type 2 (BMPR2); mRNA
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody