AUH Antibody
Product Sizes
100 ug
£582.00
OAAL00023-100UG
About this Product
- SKU:
- OAAL00023
- Additional Names:
- 3-methylglutaconyl-CoA hydratase;AU RNA binding protein/enoyl-CoA hydratase;AU RNA-binding protein/enoyl-Coenzyme A hydratase;AU-binding protein/Enoyl-CoA hydratase;AU-specific RNA-binding enoyl-CoA hydratase;itaconyl-CoA hydratase;methylglutaconyl-CoA hydratase; mitochondrial.
- translate.label.attr.clone:
- 2G12
- Clonality:
- Monoclonal
- Extra Details:
- AU-specific RNA-binding enoyl-CoA hydratase (AUH) protein binds to the AU-rich element (ARE); a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos; c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase; an enzyme involved in fatty acid degradation; and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity. A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92% identity with the human protein. It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein. Human AUH is expressed as a single mRNA species of 1.8 kb; and translated as a 40-kDa precursor protein which is subsequently processed to a 32-kDa mature form. [provided by RefSeq
- Gene Details:
- AU RNA binding methylglutaconyl-CoA hydratase
- Host:
- Mouse
- Immunogen:
- AUH (NP_001689; 44 a.a. ~ 135 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Isotype:
- IgG2a Kappa
- Protein Details:
- Homo sapiens AU RNA binding methylglutaconyl-CoA hydratase (AUH); transcript variant 1; mRNA|methylglutaconyl-CoA hydratase; mitochondrial isoform 1 precursor [Homo sapiens]
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
