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Antibodies

ACTL6A Antibody

Product Sizes
100 ug
£582.00
OAAL00004-100UG
About this Product
SKU:
OAAL00004
Additional Names:
53 kDa BRG1-associated factor A;actin-like protein 6A;actin-related protein 4;actin-related protein Baf53a;ACTL6;Arp4;arpNbeta;ARPN-BETA;BAF complex 53 kDa subunit;BAF53;BAF53A;BRG1-associated factor 53A;hArpN beta;INO80 complex subunit K;INO80K;SMARCN1.
translate.label.attr.clone:
3C4
Clonality:
Monoclonal
Extra Details:
This gene encodes a family member of actin-related proteins (ARPs); which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold; which is an ATP-binding cleft; as a common feature. The ARPs are involved in diverse cellular processes; including vesicular transport; spindle orientation; nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals; which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin; it is required for maximal ATPase activity of BRG1; and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq
Gene Details:
actin like 6A
Host:
Mouse
Immunogen:
ACTL6A (NP_817126; 1 a.a. ~ 80 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Isotype:
IgG1 Kappa
Protein Details:
actin-like protein 6A isoform 2 [Homo sapiens]|Homo sapiens actin like 6A (ACTL6A); transcript variant 2; mRNA
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody