HSD17B10 Antibody
Product Sizes
100 uL
£446.00
OAAJ07813-100UL
About this Product
- SKU:
- OAAJ07813
- Additional Names:
- 17-beta-HSD 10; 17-beta-hydroxysteroid dehydrogenase 10; 17b-HSD10; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type-2; 3-hydroxyacyl-CoA dehydrogenase type II; ABAD; CAMR; DUPXp11.22; Endoplasmic reticulum-associated amyl
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/mL
- Extra Details:
- Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P; an enzyme composed of MRPP1/TRMT10C; MRPP2/HSD17B10 and MRPP3/KIAA0391; which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta; it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human HSD17B10
- Molecular Weight:
- 27 kDa
- Purification:
- Immunogen affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
