RACGAP1 Antibody
Product Sizes
100 uL
£446.00
OAAJ07725-100UL
About this Product
- SKU:
- OAAJ07725
- Additional Names:
- CYK4; ID-GAP; HsCYK-4; MgcRacGAP
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/mL
- Extra Details:
- Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human RACGAP1
- Molecular Weight:
- 71 kDa
- Protein Details:
- Rac GTPase-activating protein 1
- Purification:
- Immunogen affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
