ITGB2 Antibody
Product Sizes
100 uL
£446.00
OAAJ07370-100UL
About this Product
- SKU:
- OAAJ07370
- Additional Names:
- LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/mL
- Extra Details:
- Integrin alpha-L/beta-2 is a receptor for ICAM1; ICAM2; ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. Integrin alpha-L/beta-2 in assosiation with ICAM3; contributes to apoptotic neutrophil phagocytosis by macrophages.
- Host:
- Rabbit
- Immunogen:
- Recombinant proteinof human ITGB2
- Molecular Weight:
- 85 kDa
- Protein Details:
- Integrin beta-2
- Purification:
- Immunogen affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
