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Antibodies

ANGPTL4 Antibody

Product Sizes
100 uL
£446.00
OAAJ07225-100UL
About this Product
SKU:
OAAJ07225
Additional Names:
NL2; ARP4; FIAF; HARP; PGAR; HFARP; TGQTL; UNQ171; pp1158
Clonality:
Polyclonal
Concentration:
1 mg/mL
Extra Details:
Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation; migration; and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis; lipid metabolism; and insulin sensitivity. In response to hypoxia; the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation .
Host:
Rabbit
Immunogen:
Recombinant protein of human ANGPTL4
Molecular Weight:
45 kDa
Protein Details:
Angiopoietin-related protein 4
Purification:
Immunogen affinity chromatography
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody