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Antibodies

ITGAL Antibody

Product Sizes
100 uL
£446.00
OAAJ06999-100UL
About this Product
SKU:
OAAJ06999
Additional Names:
CD11A; LFA-1; LFA1A
Clonality:
Polyclonal
Concentration:
1 mg/mL
Extra Details:
Integrin alpha-L/beta-2 is a receptor for ICAM1; ICAM2; ICAM3 and ICAM4. Integrin alpha-L/beta-2 is also a receptor for F11R. Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction; cytotoxic T-cell mediated killing; and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Required for generation of common lymphoid progenitor cells in bone marrow; indicating a role in lymphopoiesis . Integrin alpha-L/beta-2 in assosiation with ICAM3; contributes to apoptotic neutrophil phagocytosis by macrophages.
Host:
Rabbit
Immunogen:
Recombinant Protein of human ITGAL
Molecular Weight:
129 kDa
Protein Details:
Integrin alpha-L
Purification:
Immunogen affinity chromatography
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody