MYOC Antibody
Product Sizes
100 uL
£446.00
OAAJ06957-100UL
About this Product
- SKU:
- OAAJ06957
- Additional Names:
- GPOA; JOAG; TIGR; GLC1A; JOAG1
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/mL
- Extra Details:
- Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion; cell-matrix adhesion; cytoskeleton organization and cell migration. Promotes substrate adhesion; spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. Promotes cell migration through activation of PTK2 and the downstream phosphatidylinositol 3-kinase signaling. Plays a role in bone formation and promotes osteoblast differentiation in a dose-dependent manner through mitogen-activated protein kinase signaling. Mediates myelination in the peripheral nervous system through ERBB2/ERBB3 signaling. Plays a role as a regulator of muscle hypertrophy through the components of dystrophin-associated protein complex. Involved in positive regulation of mitochondrial depolarization. Plays a role in neurite outgrowth. May participate in the obstruction of fluid outflow in the trabecular meshwork.
- Host:
- Rabbit
- Immunogen:
- Recombinant proteinof human MYOC
- Molecular Weight:
- 57 kDa
- Protein Details:
- Myocilin
- Purification:
- Immunogen affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
