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Antibodies

ANG Antibody

Product Sizes
100 uL
£446.00
OAAJ06923-100UL
About this Product
SKU:
OAAJ06923
Additional Names:
ALS9; RAA1; HEL168; RNASE4; RNASE5
Clonality:
Polyclonal
Concentration:
1 mg/mL
Extra Details:
Binds to actin on the surface of endothelial cells; once bound; angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.
Host:
Rabbit
Immunogen:
Recombinant proteinof human ANG
Molecular Weight:
17 kDa
Protein Details:
Angiogenin
Purification:
Immunogen affinity chromatography
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody