CD44 Antibody
Product Sizes
100 uL
£446.00
OAAJ06866-100UL
About this Product
- SKU:
- OAAJ06866
- Additional Names:
- IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/mL
- Extra Details:
- Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA; and possibly also through its affinity for other ligands such as osteopontin; collagens; and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration; tumor growth and progression. In cancer cells; may play an important role in invadopodia formation. Also involved in lymphocyte activation; recirculation and homing; and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter; leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function .
- Host:
- Rabbit
- Immunogen:
- A synthetic peptideof human CD44
- Molecular Weight:
- 82 kDa
- Protein Details:
- CD44 antigen
- Purification:
- Immunogen affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
