ATXN3 Antibody
Product Sizes
100 uL
£446.00
OAAJ06849-100UL
About this Product
- SKU:
- OAAJ06849
- Additional Names:
- AT3; JOS; MJD; ATX3; MJD1; SCA3
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/mL
- Extra Details:
- Deubiquitinating enzyme involved in protein homeostasis maintenance; transcription; cytoskeleton regulation; myogenesis and degradation of misfolded chaperone substrates. Binds long polyubiquitin chains and trims them; while it has weak or no activity against chains of 4 or less ubiquitins. Involved in degradation of misfolded chaperone substrates via its interaction with STUB1/CHIP: recruited to monoubiquitinated STUB1/CHIP; and restricts the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. In response to misfolded substrate ubiquitination; mediates deubiquitination of monoubiquitinated STUB1/CHIP. Interacts with key regulators of transcription and represses transcription: acts as a histone-binding protein that regulates transcription.
- Host:
- Rabbit
- Immunogen:
- Recombinant proteinof human ATXN3
- Molecular Weight:
- 43 kDa
- Protein Details:
- Ataxin-3
- Purification:
- Immunogen affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
