TARDBP Antibody
Product Sizes
100 uL
£446.00
OAAJ06791-100UL
About this Product
- SKU:
- OAAJ06791
- Additional Names:
- ALS10; TDP-43
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/mL
- Extra Details:
- DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis; apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of human TARDBP
- Molecular Weight:
- 43 kDa
- Protein Details:
- TAR DNA-binding protein 43
- Purification:
- Immunogen affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
