ATG4C Antibody
Product Sizes
100 uL
£446.00
OAAJ06733-100UL
About this Product
- SKU:
- OAAJ06733
- Additional Names:
- APG4C; AUTL1; AUTL3; APG4-C
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/mL
- Extra Details:
- Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation . Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2; to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes; which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
- Host:
- Rabbit
- Immunogen:
- Recombinant proteinof human ATG4C
- Molecular Weight:
- 52 kDa
- Protein Details:
- Cysteine protease ATG4C
- Purification:
- Immunogen affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
