CD40LG Antibody
Product Sizes
100 uL
£446.00
OAAJ06571-100UL
About this Product
- SKU:
- OAAJ06571
- Additional Names:
- IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/mL
- Extra Details:
- Cytokine that binds to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching .
- Host:
- Rabbit
- Immunogen:
- N term -peptideof human CD40LG
- Molecular Weight:
- 29 kDa
- Purification:
- Immunogen affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
