BVES Antibody
Product Sizes
100 uL
£446.00
OAAJ06493-100UL
About this Product
- SKU:
- OAAJ06493
- Additional Names:
- POP1; HBVES; CARICK; LGMD2X; POPDC1; LGMDR25
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/mL
- Extra Details:
- Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca2+-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading . Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated; at least in part; through cAMP-binding and; probably; by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density. Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.
- Host:
- Rabbit
- Immunogen:
- Recombinant Protein of human BVES
- Molecular Weight:
- 41 kDa
- Protein Details:
- Blood vessel epicardial substance
- Purification:
- Immunogen affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
