ATF6 Antibody
Product Sizes
100 uL
£446.00
OAAJ06483-100UL
About this Product
- SKU:
- OAAJ06483
- Additional Names:
- ACHM7; ATF6A
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/mL
- Extra Details:
- Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress; the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'-ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.
- Host:
- Rabbit
- Immunogen:
- C term -peptideof human ATF6
- Molecular Weight:
- 75 kDa
- Protein Details:
- Cyclic AMP-dependent transcription factor ATF-6 alpha
- Purification:
- Immunogen affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
