EPHA3 Antibody
Product Sizes
100 uL
£446.00
OAAJ06241-100UL
About this Product
- SKU:
- OAAJ06241
- Additional Names:
- EK4; ETK; HEK; ETK1; HEK4; TYRO4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/mL
- Extra Details:
- Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells; leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regulates cell-cell adhesion; cytoskeletal organization and cell migration. Plays a role in cardiac cells migration and differentiation and regulates the formation of the atrioventricular canal and septum during development probably through activation by EFNA1. Involved in the retinotectal mapping of neurons. May also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide derived from human EPHA3
- Molecular Weight:
- 110 kDa
- Protein Details:
- Ephrin type-A receptor 3
- Purification:
- Immunogen affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
