STK24 Antibody
Product Sizes
100 uL
£446.00
OAAJ05339-100UL
About this Product
- SKU:
- OAAJ05339
- Additional Names:
- MST3; STK3; MST3B; STE20; HEL-S-95
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/mL
- Extra Details:
- Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9); p38 (MAPK11; MAPK12; MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.
- Host:
- Rabbit
- Immunogen:
- A synthesized peptide
- Molecular Weight:
- 50 kDa
- Protein Details:
- Serine/threonine-protein kinase 24
- Purification:
- Immunogen affinity chromatography
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
