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Antibodies

ARHGAP18 Antibody

Product Sizes
100 uL
£446.00
OAAJ05303-100UL
About this Product
SKU:
OAAJ05303
Additional Names:
SENEX; MacGAP; bA307O14.2
Clonality:
Polyclonal
Concentration:
1 mg/mL
Extra Details:
Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization; which in turn reduces nuclear localization of YAP1. Regulates cell shape; spreading; and migration.
Host:
Rabbit
Immunogen:
A synthesized peptide
Molecular Weight:
75 kDa
Protein Details:
Rho GTPase-activating protein 18
Purification:
Immunogen affinity chromatography
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at +4C. For long term storage; aliquot and store at -20C. Avoid freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody