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Antibodies

Anti-ER Antibody

Product Sizes
100ug
£522.00
OAAI00703-100UG
About this Product
SKU:
OAAI00703
Additional Names:
E2 receptor alpha;ER;Era;ER-alpha;ESR;ESRA;estradiol receptor;estrogen nuclear receptor alpha;estrogen receptor;estrogen receptor alpha E1-E2-1-2;estrogen receptor alpha E1-N2-E2-1-2;ESTRR;NR3A1;nuclear receptor subfamily 3 group A member 1;oestrogen receptor alpha.
Clonality:
Polyclonal
Concentration:
100ug/200ul
Extra Details:
ER (estrogen receptor) belongs to a member of the steroid receptor superfamily. It contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Throμgh its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2; respectively); ER regulates transcription by its phosphorylation at multiple sites; such as serine 104; 106; 118; 167 and 305. Phosphorylation of certain serine at ER may relate to breast cancer process and on-going treatment.
Gene Details:
estrogen receptor 1
Host:
Rabbit
Immunogen:
A synthetic peptide surrounding the epitope -KNSLA- with a phosphorylation site of Ser305 of human estrogen receptor.
Isotype:
Rabbit IgG
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody