Anti-GLEPP-1 Antibody
Product Sizes
100ug
£532.00
OAAI00688-100UG
About this Product
- SKU:
- OAAI00688
- Additional Names:
- GLEPP1;glomerular epithelial protein 1;NPHS6;osteoclastic transmembrane protein-tyrosine phosphatase;phosphotyrosine phosphatase U2;protein tyrosine phosphatase PTP-U2;PTP phi;PTPase U2;PTP-OC;PTPROT;PTPU2;PTP-U2;receptor-type tyrosine-protein phosphatase O;R-PTP-O.
- translate.label.attr.clone:
- 5F3F8
- Clonality:
- Monoclonal
- Concentration:
- 100ug/200ul
- Extra Details:
- Glomerular Epithelial Protein 1 (GLEPP-1) is a transmembrane protein tyrosine phosphatase found only in the epithelial cells of the renal glomerulus. It is localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. It may have multiple isoform-specific and tissue-specific functions; including the regulation of osteoclast production and activity; inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppresor; and decreased expression of this gene has been observed in several types of cancer. GLEPP-1 is present only in visceral glomerular cells (Podocytes). The presence of GLEPP1 may be used as a marker of podocyte integrity in various forms of glomerular injury.
- Gene Details:
- protein tyrosine phosphatase receptor type O
- Host:
- Mouse
- Immunogen:
- The recombinant fusion protein made from part of the extracellular domain of human GLEPP-1.
- Isotype:
- IgG1
- Molecular Weight:
- ~130
- Purification:
- The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
