Anti-CD 51 Monoclonal Antibody
Product Sizes
100ug
£608.00
OAAI00677-100UG
About this Product
- SKU:
- OAAI00677
- Additional Names:
- antigen identified by monoclonal antibody L230;CD51;integrin alpha-V;integrin alphaVbeta3;integrin; alpha V (vitronectin receptor; alpha polypeptide; antigen CD51);MSK8;vitronectin receptor subunit alpha;VNRA;VTNR.
- translate.label.attr.clone:
- HCD51-10C4
- Clonality:
- Monoclonal
- Concentration:
- 100ug/200ul
- Extra Details:
- CD51 is a type I integral membrane glycoprotein; known as vitronectin receptor alpha chain; or integrin alphaV. It forms heterodimer with integrin beta1 (CD29); beta3 (CD61); beta5; beta6; or beta8. CD51 contains two disulfide-linked subunits of 125 kDa and 24 kDa; and is expressed on endothelial cells; fibroblasts; macrophages; platelets; osteoclasts; neuroblastoma; melanoma; and hepatoma cells. Many extracellular matrix proteins with RGD-motifs are CD51 ligands. In association with its beta chains; CD51 binds vitronectin; von Willebrand factor; fibronectin; thrombospondin; osteopontin; fibrinogen; and laminin. CD51; as an adhesion molecule; plays important roles in leukocytes homing and rolling; mediates bone absorption and angiogenesis.
- Gene Details:
- integrin subunit alpha V
- Host:
- Mouse
- Immunogen:
- Mice were immunized with culture human melanoma cells.
- Isotype:
- IgG1
- Purification:
- The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
