Anti-CD14 Monoclonal Antibody
Product Sizes
100ug
£608.00
OAAI00676-100UG
About this Product
- SKU:
- OAAI00676
- Additional Names:
- monocyte differentiation antigen CD14;myeloid cell-specific leucine-rich glycoprotein.
- translate.label.attr.clone:
- HCD14-61D3
- Clonality:
- Monoclonal
- Concentration:
- 100ug/200ul
- Extra Details:
- CD14; also known lipopolysaccharide (LPS) receptor; is a 55 kDa glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein. It is expressed at high levels on monocytes and macrophage; and at lower levels on the surface of granulocytes and neutrophils. Some dendritic cell populations such as interfollicular dendritic cells; reticular dendritic cells; and Langerhans cells have also been reported to express CD14. CD14 is anchored to cells by linkage to GPI and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14; also binding to LPS; acts at physiological concentRation as an LPS agonist and has; at higher concentRations; an LPS antagonizing effect in cell activation. CD14 is involved in the clearance of gram-negative pathogens and in the up-regulation of adhesion molecules and cytokines expression in monocytes and neutrophils.
- Gene Details:
- CD14 molecule
- Host:
- Mouse
- Immunogen:
- Mice were immunized with culture human peripheral blood monocytes.
- Isotype:
- IgG1
- Purification:
- The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
