Anti-CD8
Product Sizes
100ug
£511.00
OAAI00640-100UG
About this Product
- SKU:
- OAAI00640
- Additional Names:
- Cluster of Differentiation 8
- translate.label.attr.clone:
- 3B5
- Clonality:
- Monoclonal
- Concentration:
- 100ug/200ul
- Extra Details:
- The CD8 antigen; also known as T8 or Leu2 or Lyt2 or T cell coreceptor; is a cell surface glycoprotein; a dimer with a molecular mass of 32 kD. It is found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cells in the context of class I MHC molecules. The T8 antigen is expressed by the suppressor/cytotoxic subset of T lymphocytes which comprise most of the cortical thymocytes and approximately 30% of peripheral blood T cells. Studies have demonstRated that increased levels of T8+ cells are associated with viral infections such as hepatitis B; Epstein-Barr; and cytomegalovirus. This Antibody may be used in the study of cell-mediated cytotoxicity and that of immunoregulation and T-lymphocyte-mediated suppression. This Antibody stains CD8 (T8) antigen suppressor/cytotoxic T lymphocytes and majority of thymocytes (approximately 80%) in frozen tissue sections.
- Gene Details:
- CD8a molecule
- Host:
- Mouse
- Immunogen:
- A recombinant protein derived from extracellular domain (22-182aa) was used as an immunogen.
- Isotype:
- IgG2a
- Purification:
- The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
