Anti-Desmin Antibody
Product Sizes
100ug
£619.00
OAAI00565-100UG
About this Product
- SKU:
- OAAI00565
- Additional Names:
- cardiomyopathy; dilated 1F (autosomal dominant);CDCD3;CSM1;CSM2;desmin;epididymis secretory sperm binding protein;intermediate filament protein;LGMD1D;LGMD1E;LGMD2R.
- Clonality:
- Polyclonal
- Concentration:
- 100ug/200ul
- Extra Details:
- Desmin is a major intermediate filament protein found exclusively in striated (skeletal or cardiac) muscle tissue. It belongs to a large family of class III intermediate filament protein; the main intermediate filamentin mature skeletal; cardiac and smooth muscle cells. Mutations in the gene encoding desmin are associated with desmin-related myopathy; a familial cardiac and skeletal myopathy (CSM); and with distal myopathies. PKC (Protein Kinase C) and cAMP-dependent protein kinase can induce disassembly of the desmin filaments by phosphorylating multiple sites at N-terminus of desmin which can affect the desmin filament structure which play a role in the regulatory process in assembly and turnover.
- Gene Details:
- desmin
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide SRL G-*T-*T -RTP corresponding to the N-terminus with a dual phosphorylated threonine (Thr76/Thr77) of human Desmin.
- Isotype:
- Rabbit IgG
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
