Anti-Villin 2/Ezrin/p81 Polyclonal Antibody
Product Sizes
100ug
£457.00
OAAI00438-100UG
About this Product
- SKU:
- OAAI00438
- Additional Names:
- CVIL;CVL;cytovillin 2;epididymis secretory protein Li 105;ezrin;HEL-S-105;p81;VIL2;villin 2 (ezrin).
- Clonality:
- Polyclonal
- Concentration:
- 100ug/200ul
- Extra Details:
- Villin 2; also known as Ezrin; p81; 80K; or cytovillin; is a cytoplasmic peripheral membrane protein which is enriched in microvilli and other cell surface structures; Villin belongs to a member of the gelsolin family of calcium-regulated actin-binding proteins. Unlike the ubiquitously expressed gelsolin; villin expression is restricted to simple epithelia of the gastrointestinal and urogenital tracts. It is localized to the apical cytoplasm and brush borders of these cells. Villin functions in the regulation of actin dynamics in the apical epithelium; capping; nucleating and/or severing actin filaments in a calcium-dependent manner and regulating cell shape in response to external stimuli. Villin serves as a tyrosine kinase substRate; and is phosphorylated in EGF-stimulated cells. This protein plays a key role in cell surface structure adhesion; migRation and organization; and it has been implicated in various Human cancers.
- Gene Details:
- ezrin
- Host:
- Rabbit
- Immunogen:
- A synthetic peptide corresponding to the C-term portion of human Ezrin protein. This sequence is identical to human; rat; mouse; dog; Monkey; zebra fish; and human origins.
- Isotype:
- Rabbit IgG
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
